Aceclofenac, Paracetamol & Chlorzoxazone (OSTAFRESH-MR)

Chlorzoxazone is a benzoxazole secondary along with mild sedative and centrally-acting muscle loosening activities. However, its exact mechanism of action is undefined, chlorzoxazone (CZ) appears to act at the spinal cord and subcortical levels of the brain to check multisynaptic reflex arcs involved in producing and maintaining muscle spasms.

Aceclofenac Paracetamol is used to treat various health issues which are as follows: -

• It is used to treat Back Pain
• It is frequently used when there is a case of ankylosing spondylitis
• Mostly used in the case of frozen shoulder
• It is used in the case of Osteoarthritis.
• It is mostly used in the case of rheumatoid arthritis
• It is also used in the case of mild to moderate fever as it contains paracetamol

Chlorzoxazone is the practice to treat muscle spasms / pain. It is generally used along with rest, physical therapy, and other treatment. It works by helping out to relax the muscles.

It is an approved drug in India but can cause side effects to some people. These include stomach pain, vomiting, skin rashes, nausea, diarrhea, constipation, etc.

Indigestion:  In the case of indigestion, patients should take tablets along with a meal. If the pain continues, talk to the doctor straight away.

Diarrhea:  Drink plenty of water and other fluids to treat the problem by replacing the loss of fluid caused by this condition.

Dizziness:   Do not drive or use any heavy machinery if the patient experiences dizziness.

• An allergic reaction that can cause swelling and a rash
• Low blood pressure, and a fast heartbeat this has happened when paracetamol is considering into a vein in your arm at the hospital.
• A blood disorders, such as leukopenia (low number of white blood cells) and thrombocytopenia (low number of platelet cells)
• Damage of liver and kidney, if you take too much (overdose) – this can be fatal in severe cases

• Upset stomach
• Drowsiness
• Tiredness
• lightheadedness
• Headache

During this medication, your urine turns orange or reddish-purple which is harmless and will disappear when the medication is stopped.

Indication of Aceclofenac Tablet:-

Aceclofenac film-coated tablets are indicated for the relief of pain and inflammation in osteoarthritis, ankylosing spondylitis, and rheumatoid arthritis.

Indication of Paracetamol Tablet:-

This drug is used to cure mild to moderate pain(such as headaches, menstrual periods, osteoarthritis, toothaches, backaches, cold/flu aches, and pain) and also to reduce fever.

Indication of Chlorzoxazone Tablet:-

Chlorzoxazone is indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomfort correlated with acute, painful musculoskeletal conditions. The mode of action of this drug has not been clearly recognized, but maybe associate with its sedative properties.